Multiple Statistical Testing

In the advent of big data such as genomics, running numerous statistical tests is unavoidable. But long comes strange statistical problems. This post investigates issues with multiple statistical testing and its solutions along with simulated data.

Humanity has never lived in better times

It is easy to be disillusioned and pessimistic about the world we live in. Bad news seems to be followed by worse news. But humanity has come a long way from the disease-ridden, impoverished, war-torn lives of our fore-fathers. Here we look at a few data-driven graphs to convince ourselves of the progress we have made over time in various aspects of life. Slow progress never makes headlines.

Read counts of RNA-Seq Spike-ins using STAR and QoRTs

A short tutorial on quantifying spike-ins used in an RNA-Seq experiment.

Structure 'Sort by Q' explained.

STRUCTURE is a popular software used by biologists to infer the population structure of organisms using genetic markers. Barplots in STRUCTURE have an option to sort individuals by Q. We explore the 'Sort by Q' option using R and Excel to figure out what it does.

A guide to elegant tiled heatmaps in R

A step-by-step guide to data preparation and plotting of simple, neat and elegant heatmaps in R using base graphics and ggplot2.